Adaptive DBS: A New Era in Parkinson’s Disease Treatment | APDA
In this article, we’re taking a closer look at the development of adaptive DBS and the hope it offers for the future of PD treatment. What is Adaptive Deep Brain Stimulation? DBS is often described as a “pacemaker for the brain.â€
Adaptive deep brain stimulation in Parkinson's disease
The following sections explain the mechanisms of aDBS in more detail, show clinical evidence supporting its efficacy, discuss the technical and practical challenges it presents, and describe future directions for its development.
From adaptive deep brain stimulation to adaptive circuit targeting - Nature
We discuss the state of the art in the adaptive and connectomic DBS fields and the research gaps that need to be addressed to unify these concepts.
Adaptive vs. Conventional Deep Brain Stimulation: One-Year Subthalamic ...
Conventional DBS (cDBS) for Parkinson’s disease uses constant, predefined stimulation parameters, while the currently available adaptive DBS (aDBS) provides the possibility of adjusting current amplitude with respect to subthalamic activity in the beta band (13–30 Hz).
Adaptive deep brain stimulation in Parkinson's disease
We review clinical evidence comparing aDBS with conventional DBS in terms of motor improvement, side-effect reduction, energy efficiency, and technical developments, including sensing-enabled device characteristics, stimulation algorithms, and potential clinical indications.
Adaptive deep brain stimulation (aDBS) - ScienceDirect
From a clinical point of view, we have reported the major findings related to symptoms management using aDBS and principal findings in animal models, showing that the implementation of closed loop adaptive deep brain stimulation can ameliorate symptom management in neurodegenerative disorders.
Clinical perspectives of adaptive deep brain stimulation
The application of stimulators implanted directly over deep brain structures (i.e., deep brain stimulation, DBS) was developed in the late 1980s and has since become a mainstream option to treat several neurological conditions.
From adaptive deep brain stimulation to adaptive circuit targeting
We discuss the state of the art in the adaptive and connectomic DBS fields and the research gaps that need to be addressed to unify these concepts.